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New warnings added on multiple diabetes drugs

This update also covers a risk evaluation and mitigation strategy for liraglutide and approval of a new PCSK9 inhibitor.
https://immattersacp.org/archives/2015/11/fda.htm
1 Nov 2015

MKSAP Quiz: Intermittent abdominal discomfort

A 61-year-old woman is evaluated for intermittent abdominal discomfort and a bloating sensation. Approximately 2 months before the swelling started, the patient had a pruritic, gradually progressive rash characterized by redness of the face, and a pruritic rash on her chest, upper back, shoulders, hands, and lateral hips. She has no muscle pain, weakness, or joint pain. Pertinent family history includes breast cancer in her mother and ovarian cancer in her grandmother. Mammogram, Pap test, and colonoscopy, all performed within the last year, were normal. Following a physical exam and lab findings, what is the most appropriate diagnostic study for this patient?.
https://immattersacp.org/archives/2013/11/mksap.htm
1 Nov 2013

Physical activity program for older adults linked to long-term improvements in function

Older adults with reduced lower-limb physical functioning treated with a 12-month, group-based physical activity and behavior maintenance program had greater improvements in function than those who received educational sessions on healthy aging, an English trial found.
https://immattersacp.org/weekly/archives/2022/03/29/1.htm
29 Mar 2022

Guideline recommends pharmacologic treatment of osteoporosis in postmenopausal women at high fracture risk

Bisphosphonates are recommended for initial treatment, although ibandronate is not recommended for reducing nonvertebral or hip fracture risk, the clinical practice guideline from the Endocrine Society stated.
https://immattersacp.org/weekly/archives/2019/04/02/4.htm
2 Apr 2019

Factor frailty into preop assessment

There's no real consensus definition when it comes to assessing frailty perioperatively, but there are risk calculators and risk indices available to help.
https://immattersacp.org/archives/2018/07/factor-frailty-into-preop-assessment.htm
1 Jul 2018

Multicomponent fall prevention programs no more effective than mailed information alone

Researchers in England compared fracture rates over 18 months among elderly participants who received advice about fall reduction by mail alone and those who received advice by mail plus an exercise-based or multifactorial intervention.
https://immattersacp.org/weekly/archives/2020/11/10/4.htm
10 Nov 2020

Early interventions overlooked in OA

Osteoarthritis has been somewhat neglected, according to a recently formed consortium that is advocating for more proactive diagnosis and intervention. Earlier screening and a less reactive approach might head off some of the worst of the difficulties and related treatment costs.
https://immattersacp.org/archives/2013/05/osteoarthritis.htm
1 May 2013

‘PharManure’ and some drugs to hate the most

Drugs that made this doctor's least-most-wanted list, presented at Internal Medicine 2012, included those that increase costs without improving care, or that raise the risk of antibiotic resistance.
https://immattersacp.org/archives/2012/06/pharmanure.htm
1 Jun 2012

PPI's benefits can outweigh their possible risks

The key to proper use of proton-pump inhibitors is monitoring patients closely to determine if they are benefitting from long-term therapy, or could potentially discontinue or reduce their dose.
https://immattersacp.org/archives/2012/10/PPIs.htm
1 Oct 2012

MKSAP Quiz: 2-week history of left-sided headaches

An 82-year-old woman is evaluated for a 2-week history of left-sided headaches with pain on chewing, accompanied by achiness in the shoulders and hips. She has no other pertinent personal or family history. She takes no medications. Following a physical exam and lab studies, what is the most appropriate immediate next step in management?
https://immattersacp.org/weekly/archives/2017/11/14/3.htm
14 Nov 2017

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