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Antifracture effects of zoledronate persist for up to 3.5 years, study suggests

Fracture rates rose from 15 per 1,000 woman-years in the last two years of a six-year trial to 24 fractures in the first two years of follow-up. In the next two years of follow-up, the rate substantially increased to 42 fractures per 1,000 woman-years.
https://immattersacp.org/weekly/archives/2024/03/12/4.htm
12 Mar 2024

Calcium, vitamin D may affect long-term health in postmenopausal women

A post hoc analysis of data from the Women's Health Initiative found that those who took calcium and vitamin D supplements had a lower risk for death from cancer and a higher risk for death from cardiovascular disease.
https://immattersacp.org/weekly/archives/2024/03/12/1.htm
12 Mar 2024

Study finds no link between elective surgery and dementia risk in seniors

Patients older than age 65 years who underwent elective surgeries had a 4.6% rate of incident dementia within five years, compared to 6.9% in matched controls who consulted with a surgeon but did not undergo surgery, a Canadian study found.
https://immattersacp.org/weekly/archives/2024/01/09/4.htm
9 Jan 2024

MKSAP Quiz: 1-year history of widespread joint, muscle pain

A 37-year-old woman is evaluated for a 1-year history of widespread joint and muscle pain, fatigue, poor sleep, and difficulty focusing. Following a physical exam and lab tests, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2024/01/09/3.htm
9 Jan 2024

MKSAP quiz: Inclusion body myositis

An 82-year-old man is seen in follow-up for inclusion body myositis. A prednisone taper over the past 4 months was completed without clinical improvement. Following a physical exam and lab test, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2023/10/24/3.htm
24 Oct 2023

Oral drug for postpartum depression approved

This column reviews recent recalls, alerts, and approvals.
https://immattersacp.org/archives/2023/10/oral-drug-for-postpartum-depression-approved.htm
1 Oct 2023

MKSAP Quiz: Follow-up for ankylosing spondylitis

A 35-year-old woman is evaluated in follow-up for a recent diagnosis of ankylosing spondylitis. Despite the use of three different NSAIDs and physical therapy, she continues to have night pain and morning stiffness/pain lasting more than 1 hour. Following a physical exam and pelvic radiograph, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2023/08/22/3.htm
22 Aug 2023

Latest updates on ACP's priorities, initiatives

ACP Spotlight offers readers a look at ACP's current top priorities and initiatives, as well as highlights from our e-newsletter, ACP Internist Weekly.
https://immattersacp.org/archives/2023/07/latest-updates-on-acps-priorities-initiatives.htm
1 Jul 2023

Colchicine linked to lower incidence of total knee, hip replacements in patients with chronic coronary artery disease

Compared to placebo, colchicine (0.5 mg once daily) was associated with a 31% lower incidence of total knee replacements and total hip replacements, an exploratory analysis of a randomized controlled trial found.
https://immattersacp.org/weekly/archives/2023/05/30/1.htm
30 May 2023

Closing the gap on osteoporosis

A new clinical guideline from ACP focuses on pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults.
https://immattersacp.org/archives/2023/05/closing-the-gap-on-osteoporosis.htm
1 May 2023

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