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Guideline recommends pharmacologic treatment of osteoporosis in postmenopausal women at high fracture risk

Bisphosphonates are recommended for initial treatment, although ibandronate is not recommended for reducing nonvertebral or hip fracture risk, the clinical practice guideline from the Endocrine Society stated.
https://immattersacp.org/weekly/archives/2019/04/02/4.htm
2 Apr 2019

Association between antidepressants and hip fracture in elderly patients may not be causal

Antidepressant users had more than twice as many hip fractures as nonusers, but this was true both in the year before and the year after starting antidepressant therapy, and the association was strongest immediately before antidepressant initiation.
https://immattersacp.org/weekly/archives/2019/01/08/1.htm
8 Jan 2019

Canagliflozin may not increase fracture risk in patients at low risk for fractures

Although canagliflozin has been linked to decreased bone mineral density, patients with type 2 diabetes who initiated the drug had similar risk of a first fracture as those who started a glucagon-like peptide-1 receptor agonist.
https://immattersacp.org/weekly/archives/2019/01/08/2.htm
8 Jan 2019

Several factors associated with hip replacement revision due to prosthetic joint infection

Preventive strategies for prosthetic joint infection that focus on hygiene, use of protective equipment, systemic antibiotics, and other similar measures could be enhanced by controlling patient-related factors.
https://immattersacp.org/weekly/archives/2018/07/31/2.htm
31 Jul 2018

Osteoporosis treatment often not started after hip fracture in elderly patients, study finds

The study found a continuous decline in starting osteoporosis treatment after hip fracture from 2004 to 2015, as well as a clinically meaningful reduction in rate of subsequent nonvertebral fracture in patients who did begin treatment versus those who did not.
https://immattersacp.org/weekly/archives/2018/07/24/4.htm
24 Jul 2018

Solving mysterious chronic cough cases

Chronic cough is the third most common reason for ambulatory care visits, but not all affected patients can receive specialist care. A few pearls can help uncover the origins of the condition.
https://immattersacp.org/archives/2018/07/solving-mysterious-chronic-cough-cases.htm
1 Jul 2018

Factor frailty into preop assessment

There's no real consensus definition when it comes to assessing frailty perioperatively, but there are risk calculators and risk indices available to help.
https://immattersacp.org/archives/2018/07/factor-frailty-into-preop-assessment.htm
1 Jul 2018

Nondrug treatments assessed for chronic pain relief

Most effects were small and long-term evidence was sparse, and while there was no evidence suggesting serious harms from any of the interventions studied, data on harms were limited.
https://immattersacp.org/weekly/archives/2018/06/19/4.htm
19 Jun 2018

MKSAP Quiz: Evaluation for a new-patient visit

A 55-year-old woman is evaluated for a new-patient visit. Medical history is significant for an eating disorder. Although she has maintained a normal weight for the past 20 years, she notes that prior to that time her weight would fluctuate in a range correlating with BMIs of 17 to 19. Family history is significant for postmenopausal osteoporosis in her mother. Following a physical exam and lab studies, what is the most appropriate management of this patient?
https://immattersacp.org/weekly/archives/2018/03/27/3.htm
27 Mar 2018

Opioids not superior to nonopioid analgesics for back pain, hip or knee osteoarthritis

There was no significant difference between groups in pain-related function, and while pain intensity was significantly better in the nonopioid group, the result did not reach a clinically predetermined level of importance.
https://immattersacp.org/weekly/archives/2018/03/13/4.htm
13 Mar 2018

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