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Arthroplasty associated with increased risk of heart attack in early postoperative period

The immediate postoperative risk of myocardial infarction following total joint arthroplasty may have been previously underappreciated, authors noted.
https://immattersacp.org/weekly/archives/2015/09/01/2.htm
1 Sep 2015

Guidance issued on antibiotic use, fall prevention in long-term care

Antibiotic recommendations from the Centers for Disease Control and Prevention address leadership commitment, accountability, drug expertise, policy and practice change, tracking and reporting antibiotic use and outcomes, and education.
https://immattersacp.org/weekly/archives/2015/09/22/4.htm
22 Sep 2015

Calcium intake does not appear to decrease fracture risk in older patients

A new study indicates that calcium supplements with or without vitamin D do not protect older people in general from fractures, and an editorialist suggests that 700 to 800 mg of dietary calcium daily for adults is probably enough.
https://immattersacp.org/weekly/archives/2015/10/06/1.htm
6 Oct 2015

New warnings added on multiple diabetes drugs

This update also covers a risk evaluation and mitigation strategy for liraglutide and approval of a new PCSK9 inhibitor.
https://immattersacp.org/archives/2015/11/fda.htm
1 Nov 2015

Fall, fracture risk may be increased with prostate-selective alpha antagonists in older men

Men 66 years of age and older who had filled a first outpatient prescription for tamsulosin, alfuzosin, or silodosin were compared with men who had not.
https://immattersacp.org/weekly/archives/2015/11/03/2.htm
3 Nov 2015

Central obesity may increase mortality risk in those with normal BMI

Body mass index is limited as a sole measure of adiposity in clinical practice, in part because it makes no distinction between fat and lean mass, an editorial noted.
https://immattersacp.org/weekly/archives/2015/11/10/4.htm
10 Nov 2015

Weighing the options for bariatric surgery

Bariatric surgery may be an option for severely obese patients for whom lifestyle changes are not enough. Internists can set up expectations that may improve postsurgical outcomes.
https://immattersacp.org/archives/2016/01/obesity.htm
1 Jan 2016

Warning on HCV treatments; more cancer drugs approved

This update also covers a warning that combination drugs can cause serious liver injury and approval of new drugs for metastatic non-small-cell lung cancer that has progressed after other treatments.
https://immattersacp.org/archives/2016/01/fda.htm
1 Jan 2016

Guidance issued for long-term bisphosphonate use

The authors noted that the risk of atypical femoral fractures is low, with an incidence of up to 50 per 100,000 person-years during the first 5 years of bisphosphonate use, resulting in a clear positive benefit/risk ratio within this time frame.
https://immattersacp.org/weekly/archives/2016/01/26/1.htm
26 Jan 2016

Repeat bone mineral density tests during osteoporosis treatment may help identify women at increased fracture risk, study finds

Monitoring bone mineral density in routine clinical practice may identify women with a suboptimal response to osteoporosis treatment who would benefit from closer follow-up, researchers noted.
https://immattersacp.org/weekly/archives/2016/07/19/1.htm
19 Jul 2016

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