Current Issue


Varenicline plus counseling improved smoking quit rates compared to counseling alone

In a randomized, double-blind trial of Black adults who smoked daily, participants who received varenicline in addition to counseling had significantly higher odds of smoking abstinence after 26 weeks than those who received counseling and placebo.

Nirmatrelvir/ritonavir rarely leads to rebound, doesn't help average-risk patients, studies find

A retrospective analysis found that symptom rebound occurred in less than 1% of high-risk COVID-19 patients treated with nirmatrelvir/ritonavir, while the manufacturer reported that the drug didn't show significant benefit in average-risk patients.

MKSAP Quiz: Involuntary urine loss with coughing

A 68-year-old woman is evaluated for involuntary urine loss that occurs with coughing, sneezing, and laughing and occasionally with physical exertion. She has no dysuria, urinary frequency, hematuria, or nocturia but does report vaginal dryness and dyspareunia. She performs pelvic floor muscle training exercises four times daily. Following a physical exam and pelvic exam, what is the most appropriate management?

Binge drinking shows potential to predict alcohol problems in people who drink moderately

Compared with a regular pattern of drinking, a binge pattern of drinking was independently and significantly associated with an increase in the number of alcohol problems nine years later, a study found.

ACP issues proposal to realign health care delivery, reimbursement for greater equity

The College issued seven policy recommendations on reforming payment programs, including prioritizing underserved patient populations, addressing value in health care, and achieving greater equity.

Reminder: Register now for ACP's Board Prep Course this summer

The course will take place July 11-15 in Arlington, Va. A live virtual format is available.

Vote for your favorite entry

ACP Internist Weekly's cartoon caption contest continues. Readers can vote for their favorite caption to determine the winner.