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First medication for severe frostbite approved

This column reviews recent recalls, alerts, and approvals.
https://immattersacp.org/archives/2024/04/first-medication-for-severe-frostbite-approved.htm
1 Apr 2024

Lung cancer screening led to more downstream procedures, complications in practice than in research

In clinical practice, 31.9% of patients screened for lung cancer underwent downstream imaging and 2.8% had downstream procedures. Those undergoing invasive procedures after abnormal findings had a 30.6% complication rate, compared to 17.7% in the National Lung Screening Trial.
https://immattersacp.org/weekly/archives/2024/01/09/1.htm
9 Jan 2024

MKSAP Quiz: 2-week history of heat intolerance in pregnancy

A 32-year-old woman is evaluated in the first trimester of pregnancy for a 2-week history of heat intolerance, palpitations, and tremulousness. Her only medication is folic acid. Following a physical examination and laboratory studies, what is the most appropriate diagnostic test?
https://immattersacp.org/weekly/archives/2024/01/23/3.htm
23 Jan 2024

Testosterone may not decrease fracture risk in hypogonadism

A substudy of an industry-funded randomized trial in men with hypogonadism found that 3.50% of those assigned to testosterone and 2.46% assigned to placebo had a clinical fracture after 3.19 years of follow-up.
https://immattersacp.org/weekly/archives/2024/01/23/2.htm
23 Jan 2024

Latest updates on ACP's priorities, initiatives

ACP Spotlight offers readers a look at ACP's current top priorities and initiatives, as well as highlights from our e-newsletter, I.M. Matters Weekly from ACP.
https://immattersacp.org/archives/2024/02/latest-updates-on-acps-priorities-initiatives.htm
1 Feb 2024

New guideline on evaluating neck masses offers imaging, biopsy advice

Among other recommendations, clinicians should order neck CT or MRI with contrast in patients with a neck mass who are thought to be at increased risk for malignancy.
https://immattersacp.org/weekly/archives/2017/09/19/2.htm
19 Sep 2017

Phase 3 trial shows efficacy of donanemab for Alzheimer disease

In an industry-funded, placebo-controlled trial of patients with early symptomatic Alzheimer disease and amyloid and tau pathology, patients on the investigational drug donanemab showed significant slowing in worsening on the integrated Alzheimer Disease Rating Scale score.
https://immattersacp.org/weekly/archives/2023/07/25/2.htm
25 Jul 2023

Supplemental imaging may not be necessary in all women with dense breasts, study finds

Supplemental imaging may not be necessary for all women with dense breasts on mammography, according to a new study.
https://immattersacp.org/weekly/archives/2015/05/19/1.htm
19 May 2015

MKSAP Quiz: Evaluation for intermittent, bright red blood per rectum

A 51-year-old man is evaluated for intermittent, bright red blood per rectum of 10 weeks' duration. Following a physical exam and other tests and imaging of a nonobstructing lesion at 10 cm from the anal verge, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2023/05/09/3.htm
9 May 2023

MKSAP Quiz: Occasional premature heartbeats

A 72-year-old man is evaluated during a routine physical examination. He feels well and reports no exertional limitations. Following a physical exam, heart sounds are regular, with occasional premature beats associated with cannon a waves on neck examination. Following tests, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2023/05/30/3.htm
30 May 2023

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