Search results for "Fracture risk"
Testosterone may not decrease fracture risk in hypogonadism
A substudy of an industry-funded randomized trial in men with hypogonadism found that 3.50% of those assigned to testosterone and 2.46% assigned to placebo had a clinical fracture after 3.19 years of follow-up.
https://immattersacp.org/weekly/archives/2024/01/23/2.htm
23 Jan 2024
Closing the gap on osteoporosis
A new clinical guideline from ACP focuses on pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults.
https://immattersacp.org/archives/2023/05/closing-the-gap-on-osteoporosis.htm
1 May 2023
MKSAP Quiz: Evaluation after a fall and surgery
A 72-year-old man is evaluated following surgical fixation of a right distal radius fracture after a fall. A dual-energy x-ray absorptiometry scan performed 2 years ago showed low bone mineral density. Alendronate weekly was initiated after the scan, and he has been adherent to therapy. What is the most appropriate management?
https://immattersacp.org/weekly/archives/2024/04/30/3.htm
30 Apr 2024
Vitamin D did not lower fracture risk in generally healthy patients, study finds
A new analysis of a large trial found no difference in total fractures, nonvertebral fractures, or hip fractures by whether men 50 years of age or older and women 55 years of age or older were randomized to vitamin D or placebo.
https://immattersacp.org/weekly/archives/2022/08/02/1.htm
2 Aug 2022
Bisphosphonates associated with lower fracture risk, not associated with mortality
Lower mortality rates linked to bisphosphonates in previous observational studies might be due to direct biological effects of treatment, authors of a recent meta-analysis noted.
https://immattersacp.org/weekly/archives/2019/08/27/4.htm
27 Aug 2019
Subclinical hypothyroidism prompts personalized decisions
For diagnosing and managing subclinical hypothyroidism, clinical context such as age and symptoms matter, even in the face of an incomplete understanding of the condition.
https://immattersacp.org/archives/2021/02/subclinical-hypothyroidism-prompts-personalized-decisions.htm
1 Feb 2021
Traumatic fractures associated with subsequent fracture risk in postmenopausal women
Data from the Women's Health Initiative suggest that either a high-trauma or low-trauma fracture warrants evaluation for osteoporosis and counseling about fracture risk.
https://immattersacp.org/weekly/archives/2021/06/15/4.htm
15 Jun 2021
Canagliflozin may not increase fracture risk in patients at low risk for fractures
Although canagliflozin has been linked to decreased bone mineral density, patients with type 2 diabetes who initiated the drug had similar risk of a first fracture as those who started a glucagon-like peptide-1 receptor agonist.
https://immattersacp.org/weekly/archives/2019/01/08/2.htm
8 Jan 2019
A defense of proton-pump inhibitors
Data on their risks may seem persuasive, but one expert is not convinced.
https://immattersacp.org/archives/2019/01/a-defense-of-proton-pump-inhibitors.htm
1 Jan 2019
Atypical femur fracture risk increases with longer bisphosphonate use, drops after discontinuation
Researchers studied women ages 50 years or older who took bisphosphonates and were enrolled in the Kaiser Permanente Southern California health care system.
https://immattersacp.org/weekly/archives/2020/08/25/3.htm
25 Aug 2020