Direct antiglobulin (Coombs) test:. Negative. A bone marrow aspiration reveals a “dry tap.” A peripheral blood smear and bone marrow biopsy are shown.
A 49-year-old woman is evaluated for a 6- month history of exertional dyspnea and nonproductive cough that had an insidious onset. She has not noticed any particular triggers for her cough. She has no history of asthma, airway disease, reflux, or
A 62-year-old man undergoes a routine examination. He notes increasing fatigue of 8 months' duration but states he can perform his usual daily activities. He has no fever, night sweats, anorexia, or weight loss. The medical history is noncontributory
A radiograph of the hand is shown. Which of the following is the most appropriate diagnostic test to perform next? ... Measurement of transferrin saturation is the most appropriate diagnostic test to perform next in this patient.
A 35-year-old woman is evaluated for worsening thrombocytopenia; she is pregnant at 36 weeks' gestation. Medical history is significant for immune thrombocytopenic purpura. Previous platelet counts during this pregnancy have been 80,000 to
A 37-year-old woman is evaluated in the emergency department for the acute onset of pain after 2 weeks of bloody diarrhea. The diarrhea has escalated to 15 times per day. She has ulcerative colitis that was diagnosed 2 years ago. She currently takes
A 47-year-old man is evaluated for a skin eruption. Approximately 2 weeks ago, his wife noted an erythematous macule on his back. Over the ensuing week, the site became progressively larger. He notes mild fatigue but no fevers. He recently returned
A 55-year-old white man has a several-year history of epigastric pain and daily heartburn without dysphagia or weight loss.
A 26-year-old man is admitted to the emergency department with a 3-day history of dysuria with yellow urethral discharge. Following a physical exam and a Gram stain of urethral discharge, what is the most appropriate treatment?.
A 72-year-old man is evaluated for a 1-year history of progressively impaired gait and balance. He reports that he walks more slowly and is not as agile as he used to be, attributing a recently increased number of falls to not paying enough