The drug's safety and efficacy were evaluated in a clinical trial with more than 14,000 patients, in which it showed similar ability to warfarin in preventing stroke. ... Given the conflicting nature of the existing research findings on this issue, the
Photo by ThinkStock. A drug safety communication that canagliflozin (Invokana, Invokamet) causes an increased risk of leg and foot amputations. ... A drug safety communication about gadolinium-based contrast agents for MRI. An FDA review, initiated in
a drug safety expert and consultant in Chapel Hill, N.C. ... Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol.
A drug safety communication that hepatitis C medicines have led to rare cases of worsening liver function or liver failure in some patients. ... The drug was originally approved in 2014 to treat adults with idiopathic pulmonary fibrosis.